Week of October 5 - October 9, 2009
Tuesday, October 6, 2009
3:45 PM TENURED FACULTY MEETING 459 MSC
Wednesday, October 7, 2009
3:30 PM Calculus Seminar 459 MSC
Thomas Hern, BGSU
Discussion on tangent lines and collapse metaphors (pp 409-413)
Thursday, October 8, 2009
4:00 PM Advisory Committee Meeting 400 MSC
Friday, October 9, 2009
3:30 PM COLLOQUIUM 459 MSC
Dr. Nan Lin, Washington State University at St. Louis
An information criterion for order-restricted inference and
its application to clustering short time-course microarray data
Abstract : Techniques of statistical inference under order restrictions
have been successfully used in many areas in statistics. We consider the
problem of selecting an order restriction profile out of a set of candidate
profiles. Existing information criteria can only be used with simple
ordering, such as monotone increasing or decreasing profiles. We developed
a new information criterion for order-restricted inference applicable to
general order restrictions, and showed its consistency in selecting the
correct order restriction profile. This new information criterion is also
successfully applied to clustering short time-course microarray data. We
first define candidate gene clusters using the order restriction profile
over the mean expression across time. A gene is then assigned to the best
matched profile/cluster determined by our new information
criterion. Compared to other existing clustering algorithms for short
time-course microarray data, the information criterion-based clustering
provides competitive clustering accuracy and is computationally more
efficient.
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